Confocal Microscopy

December 29, 2021

Stradus Laser in NicoLase

Diode laser units are convenient for fluorescence microscopy and super-resolution microscopy due to their high power and ease of use. A couple dozen lines are avaliable from most makers to cover UV through mid-IR applications. With the addition of direct modulation avaliable on nearly all modern units there’s no need for an AOTF or other tuning or power modulation control in addition to the diodes themselves.

The NicoLase is built primarily around Vortran Stradus laser diode units. These are a standardized size for each line, reasonably priced, and produce a large amount of power for their size and cost. Nearly all produce enough power for dSTORM work. These units can be digitally modulated at a high rate (usually up to 2 MHz) and potentially analog modulated if desired. I don’t have any financial reason for recommending these units, just a satisfied customer.